Celebrities! They are glamorous, talented, rich, and famous – but they have also been sleep-deprived and frustrated parents of colicky babies. If you think celebrity moms and dads are immune to the colic curse, think again!

About 1 out of 5 babies develop colic, which means the odds are stacked against even the most famous celebrity babies. While many superstars in the spotlight want their lives to appear picture-perfect, some have been brave enough to share that their own infants suffered from bouts of colic and inconsolable crying. Even His Highness, Prince George gave his Duke and Duchess parents their fair share of sleepless nights. Hollywood royalty Brad and Angelina resorted to hiring an entire medical team to assist with the care of infant twins Vivienne and Knox who would howl in pain immediately after feedings.

Colic can be defined as excessive crying or fussiness, usually in the late afternoon. It starts around 2 weeks and generally resolves or is resolving by 12 weeks. Rarely does it endure past six months of age. Pediatricians often use Wessel’s criteria to define colic: Crying for 3 hours per day, at least 3 times a week for at least 3 weeks (for non-medical reasons)–though in practice, colic may be more loosely defined.

Some associated symptoms of colic may be clenching of the fists, arching of the back, or tensing of the abdomen. Bouts tend to come on suddenly and end suddenly, and the cry may sound more intense to parents. Colicky babies may be extremely difficult to console. So who are the Top Five Most Famous Colicky Babies?

Prince George of Cambridge

Kate Middleton and Prince William (The Duke and Duchess of Cambridge’s) newborn Prince George¹ reportedly spent his first few months with colic—crying constantly and refusing to sleep through the night.

Vivienne and Knox

Of course two colic-suffering newborns along with four other children at home would cause anyone major stress! After their twins, Vivienne and Knox^2,3, were diagnosed with colic, Brad and Angelina had their own medical team stay with them at the family’s villa in France. They also had another doctor and nurse on 24-hour call.

Jaxon

Former star of Laguna Beach and The Hills, Kristin Cavallari, confesses that her second son Jaxon⁴ had colic, just like she did.

Charlie

Former “Scrubs” star Sarah Chalke revealed that her son Charlie⁵ had colic his first three months of life. “I did not sit down… literally just carried him for three month’s straight.”

So while most of the world is not be able to afford to fly in a personal medical team for round-the-clock colic monitoring, if you’ve been a parent of a colicky baby, at least you know you’re in good company.